| Exceptionally Low Extractable Levels
A filter is designed to increase accuracy by removing unwanted particles. However, the wrong filter can be a source of contaminants called extractables that elute into the sample from the filter device. These undesired artifacts jeopardize analytical results. Some extractable concerns include coelution, false quantitation, and extraneous peaks.
The specific quality of raw materials, amount of quality control, membrane extraction procedures, and post treatments all affect the resultant membrane properties and amount of extractable materials. Pall specifically selects the highest grade of materials and performs rigorous extraction methods on our membrane products to hinder the occurrence of undesired artifacts. Choosing membranes that are compatible with your fluids and experimental conditions will reduce/eliminate extractables.
Certified Syringe Filters
Pall's HPLC certification ensures that analytical results will not be compromised by extractable filter materials. To verify low levels of UV-detectable extractables, samples of the entire HPLC Acrodisc® PSF syringe filter line are randomly taken and tested for compatibility with common solvents using an HPLC (does not include HT Tuffryn®, Versapor® or Supor® membrane versions).
Pall certifies Ion Chromatography (IC) Acrodisc PSF syringe filters have been tested using a highly sensitive IC protocol to monitor inorganic extractables. Actual background levels of filter extractables are typically less than 20 ppb for chloride, 6 ppb for nitrate, 1 ppb for phosphate, and 10 ppb for sulfate.
Choose the Best Filter for Your Application
These selection guides can assist you in your filter selection:
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| Applications |
Tests |
Applicable Filtration Products |
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| Pharmaceutical Finished Product |
Tablet Pre-formulation, Candidate Evaluation, Tablet and Capsule Assay, Tablet Stability, Drug Assay, Blend Uniformity, Dissolution Testing, Dosage Form Development, Particulate Removal, Sample Clarification |
Acrodisc PSF Syringe Filters, Acrodisc Syringe Filters, Membrane Disc Filters |
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| Pharmaceutical Raw Materials, Food and Beverage |
Analytical Sample Preparation |
Acrodisc PSF Syringe Filters, AcroPrep 24 Filtration System, AcroPrep 96 Filter Plates, Nanosep MF Centrifugal Devices, SolVac Filter Holder, Glass Filter Funnels, Membrane Disc Filters |
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| HPLC |
Sample Preparation, Mobile Phase Filtration |
Acrodisc PSF Syringe Filters, AcroPrep 24 Filtration System, AcroPrep 96 Filter Plates, Nanosep MF Centrifugal Devices, SolVac Filter Holder, Glass Filter Funnels, Membrane Disc Filters |
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| Ion Chromatography |
Sample Preparation |
Acrodisc PSF Syringe Filters with IC Membrane, Acrodisc Syringe Filters with IC Membrane |
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| GC |
Sample Preparation |
Acrodisc PSF Syringe Filters with PTFE Membrane, Acrodisc Syringe Filters with PTFE Membrane |
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